Hi everyone, happy 4th of July tomorrow!

I wanted to post some additional information that was sent to me regarding the recent PML cases that have been linked to Tysabri..., as to prior treatments involving immunomodulators and/or very strong immunosuppressants, please note the following with regard to the Tysabri/PML chart that will be updated at a later time (my friend is currently on vacation for the next 10 days so it will have to be updated later)..., but specifically, the patients listed in the chart:

#7. Prior use of Rebif, Avonex, and Copaxone.

#8. Prior use of interferon beta 1-a (Avonex), and mitoxantrone (Novantrone).

#9. Prior use of Avonex, Rebif, and Novantrone.

#10. Prior use of interferon-beta, glatiramer acetate, and IVIG.

I am still waiting to receive information regarding prior use of medications for patient #6. It is most strange that no "prior treatments" information is given (and I'm not sure I'll ever receive this information). Once again, please note the prior use of very strong immunosuppressants and treatments such as Novantrone & IVIG are designed to suppress the immune system, and the different ABCRs were previously used to modulate the immune system.

Again, 8 out of the 10 new cases of PML occurred outside the US.

The above information can be found on the Élan website under Tysabri for Crohn's disease. Here is the Tysabri/PML chart which still needs to be updated:

http://pietynorwit.com/Tytable.htm

Have a wonderful and safe holiday tomorrow everyone!

((((hugs))))
Love, Lauren :)